Actin-Related Protein 3B (ACTR3B) Antibody
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Description
ACTR3B Antibody is a Rabbit Polyclonal against ACTR3B.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Actin-Related Protein 3B (ACTR3B) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 20 µl |
| Size 2 | 50 µl |
| Size 3 | 100 µl |
| Size 4 | 200 µl |
| Size 5 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9P1U1 |
| Gene ID | 57180 |
| NCBI Accession | NP_001035225.1, NM_001040135.2, NP_065178.1, NM_020445.5 |
| Alias | ACTR3B,ARP11,ARP3BETA |
| Background | Antibody anti-ACTR3B |
| Status | RUO |
Descripción
ACTR3B is a paralog of ACTR3 but has specialized tissue-specific roles, particularly in the brain and immune system. Like ACTR3, it contributes to actin filament nucleation and remodeling as part of ARP2/3-like complexes. However, ACTR3B may have unique regulatory interactions, enabling fine-tuning of cytoskeletal dynamics in specific cellular environments. Its expression is critical for neuronal development and immune cell activation. Defects in ACTR3B have been associated with neurological impairments, suggesting its unique role in actin-mediated processes.
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