Actin Related Protein 3 (ACTR3) Antibody (Biotin)
169€ (20 µg)
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935106861
info@markelab.com
name
Actin Related Protein 3 (ACTR3) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx314676
tested applications
ELISA
Description
ACTR3 Antibody (Biotin) is a Rabbit Polyclonal against ACTR3 conjugated to Biotin.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Actin Related Protein 3 (ACTR3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P61158 |
| Gene ID | 10096 |
| OMIM | 604222 |
| Alias | ACTR3,ARP3 |
| Background | Antibody anti-ACTR3 |
| Status | RUO |
Descripción
ACTR3 functions alongside ACTR2 as part of the ARP2/3 complex, driving actin filament branching and nucleation. Structurally, ACTR3 forms a dimer with ACTR2 to create a template for new filament growth. It plays a fundamental role in cytoskeletal remodeling processes, such as cell motility, intracellular trafficking, and immune cell function. ACTR3 is indispensable for processes like lamellipodia extension during cell migration. Mutations in ACTR3 are linked to developmental abnormalities, immune deficiencies, and impaired wound healing due to defective actin polymerization.
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