Actin-related protein 3 (ACTR3) Antibody
299€ (50 µl)
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Name
Actin-related protein 3 (ACTR3) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx402108
Tested Applications
ELISA, WB
Description
Actin-related protein 3 (ACTR3) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human, Mouse, Rat ACTR3.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Actin-related protein 3 (ACTR3) Immunogen: A synthesized peptide derived from human Arp3 |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/5000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Expression | Recombinant |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P61158 |
| Alias | ACTR3,ARP3 |
| Background | Antibody anti-ACTR3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ACTR3 functions alongside ACTR2 as part of the ARP2/3 complex, driving actin filament branching and nucleation. Structurally, ACTR3 forms a dimer with ACTR2 to create a template for new filament growth. It plays a fundamental role in cytoskeletal remodeling processes, such as cell motility, intracellular trafficking, and immune cell function. ACTR3 is indispensable for processes like lamellipodia extension during cell migration. Mutations in ACTR3 are linked to developmental abnormalities, immune deficiencies, and impaired wound healing due to defective actin polymerization.
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