Actin-Like Protein 7A (ACTL7A) Antibody
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Description
Actin-Like Protein 7A (ACTL7A) Antibody is a Rabbit polyclonal antibody for the detection of Human Actin-Like Protein 7A (ACTL7A).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Actin-Like Protein 7A (ACTL7A) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Y615 |
| Gene ID | 10881 |
| NCBI Accession | NP_006678.1 |
| Alias | SPGF86 |
| Background | Antibody anti-ACTL7A |
| Status | RUO |
Descripción
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ACTL7A antibody
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Actin Like 7A (ACTL7A) Antibody
ACTL7A is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. ACTL7A (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known.
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