Actin-Binding LIM Protein 3 (ABLIM3) Antibody

Este producto es parte de ABLIM - Actin-Binding LIM Protein
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169€ (20 µg)

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935106861
info@markelab.com
name
Actin-Binding LIM Protein 3 (ABLIM3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx301119
tested applications
ELISA, IHC, IF/ICC

Description

ABLIM3 Antibody is a Rabbit Polyclonal against ABLIM3.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Actin-Binding LIM Protein 3 (ABLIM3)
Host
Rabbit
Reactivity
Human
Recommended Dilution
IHC: 1/20 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA, IHC, IF/ICC
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
O94929
Gene ID
22885
NCBI Accession
NP_001287944.1, NM_001301015.2
OMIM
611305
Alias
HMFN1661
Background
Antibody anti-ABLIM3
Status
RUO

Descripción

ABLIM3 is an actin-associated protein that integrates cytoskeletal organization with intracellular signaling. Like other members of the ABLIM family, it contains LIM domains that mediate interactions with cytoskeletal and regulatory proteins, as well as actin-binding regions that anchor it to the cytoskeleton. ABLIM3 is expressed in tissues such as the heart and muscles, where it contributes to actin filament stability, cell adhesion, and mechanotransduction. It is involved in processes such as cell migration, signaling, and cytoskeletal dynamics, playing a role in maintaining the structural integrity of contractile tissues. Dysregulation of ABLIM3 has been linked to cardiac abnormalities and diseases involving impaired cytoskeletal function. Its ability to bridge actin filament organization with regulatory pathways underscores its critical role in cellular function and structural integrity.
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