Actin-Associated LIM Protein / ALP (PDLIM3) Antibody
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Description
PDLIM3 Antibody is a Rabbit Polyclonal Antibody against PDLIM3.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Actin-Associated LIM Protein / ALP (PDLIM3) |
| Host | Rabbit |
| Reactivity | Mouse |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q53GG5 |
| Gene ID | 27295 |
| NCBI Accession | NP_001107579.1 |
| Background | Antibody anti-PDLIM3 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. This gene is found near a region of chromosome 4 that has been implicated in facioscapulohumeral muscular dystrophy, but this gene does not appear to be involved in the disease. Two transcript variants encoding different isoforms have been found for this gene.
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