Abhydrolase Domain Containing 6 (ABHD6) Antibody (Biotin)

Este producto es parte de ABHD - Abhydrolase Domain Containing
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169€ (20 µg)

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935106861
info@markelab.com
name
Abhydrolase Domain Containing 6 (ABHD6) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx336584
tested applications
ELISA

Description

ABHD6 Antibody (Biotin) is a Rabbit Polyclonal against ABHD6.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Abhydrolase Domain Containing 6 (ABHD6)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Biotin
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9BV23
Gene ID
57406
Alias
ABHD6, Monoacylglycerol lipase ABHD6
Background
Antibody anti-ABHD6
Status
RUO

Descripción

ABHD6 is a serine hydrolase that modulates lipid signaling by hydrolyzing monoacylglycerols, including 2-arachidonoylglycerol (2-AG), a key endocannabinoid. Through its regulation of 2-AG levels, ABHD6 influences cannabinoid receptor signaling, which affects processes such as pain perception, appetite, and inflammation. ABHD6 is expressed in multiple tissues, including the brain, pancreas, and immune cells, where it plays roles in synaptic activity, glucose homeostasis, and immune responses. It has also been implicated in neuroinflammation and metabolic disorders, with potential links to diseases such as Alzheimer’s and diabetes. Structurally, ABHD6’s hydrolase domain is specialized for monoacylglycerol hydrolysis, making it a key regulator of endocannabinoid tone. As a critical enzyme in lipid signaling and metabolism, ABHD6 is a promising therapeutic target for treating neurodegenerative diseases, metabolic conditions, and chronic pain.

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