Abhydrolase Domain Containing 6 (ABHD6) Antibody
221€ (50 µg)
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Name
Abhydrolase Domain Containing 6 (ABHD6) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx328103
Tested Applications
ELISA, WB, IF/ICC
Description
ABHD6 Antibody is a Rabbit Polyclonal against ABHD6.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Abhydrolase Domain Containing 6 (ABHD6) Immunogen: Synthesized peptide derived from the Internal region of human ABHD6. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/20000, WB: 1/500 - 1/2000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BV23 |
| Gene ID | 57406 |
| Alias | ABHD6, Monoacylglycerol lipase ABHD6 |
| Background | Antibody anti-ABHD6 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ABHD6 is a serine hydrolase that modulates lipid signaling by hydrolyzing monoacylglycerols, including 2-arachidonoylglycerol (2-AG), a key endocannabinoid. Through its regulation of 2-AG levels, ABHD6 influences cannabinoid receptor signaling, which affects processes such as pain perception, appetite, and inflammation. ABHD6 is expressed in multiple tissues, including the brain, pancreas, and immune cells, where it plays roles in synaptic activity, glucose homeostasis, and immune responses. It has also been implicated in neuroinflammation and metabolic disorders, with potential links to diseases such as Alzheimer’s and diabetes. Structurally, ABHD6’s hydrolase domain is specialized for monoacylglycerol hydrolysis, making it a key regulator of endocannabinoid tone. As a critical enzyme in lipid signaling and metabolism, ABHD6 is a promising therapeutic target for treating neurodegenerative diseases, metabolic conditions, and chronic pain.
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