72 kDa Inositol Polyphosphate 5-Phosphatase (INPP5E) Antibody
208€ (20 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
72 kDa Inositol Polyphosphate 5-Phosphatase (INPP5E) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx003688
Tested Applications
ELISA, WB
Description
INPP5E Antibody is a Rabbit Monoclonal antibody against INPP5E. The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. Studies of the mouse counterpart suggest that this protein may hydrolyze phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,5-bisphosphate on the cytoplasmic Golgi membrane and thereby regulate Golgi-vesicular trafficking. Mutations in this gene cause Joubert syndrome; a clinically and genetically heterogenous group of disorders characterized by midbrain-hindbrain malformation and various associated ciliopathies that include retinal dystrophy, nephronophthisis, liver fibrosis and polydactyly.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: 72 kDa Inositol Polyphosphate 5-Phosphatase (INPP5E) Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CD81. |
| Host | Rabbit |
| Reactivity | Mouse, Rat |
| Assay Type | Concentration: > 0.2 mg/ml |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/1000 - 1/6000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 26 kDa Observed MW: 22 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 0.05% BSA, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NRR6 |
| Gene ID | 56623 |
| Background | Antibody anti-INPP5E |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Productos relacionados
72 kDa Inositol Polyphosphate 5-Phosphatase (INPP5E) Antibody
INPP5E Antibody is a Rabbit Monoclonal antibody against INPP5E. The protein encoded by this gene is an inositol 1,4,5-tr…
Ver producto
72 kDa Inositol Polyphosphate 5-Phosphatase (INPP5E) Antibody
Inositol Polyphosphate-5-Phosphatase, 72 Kda Antibody is a Rabbit Polyclonal antibody against Inositol Polyphosphate-5-P…
Ver producto
72 kDa Inositol Polyphosphate 5-Phosphatase (INPP5E) Antibody
INPP5E Antibody is a Rabbit Polyclonal against INPP5E.…
Ver producto