5-hydroxytryptamine receptor 3E (HTR3E) Antibody (Biotin)
260€ (50 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
5-hydroxytryptamine receptor 3E (HTR3E) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx343564
tested applications
ELISA
Description
5-hydroxytryptamine receptor 3E (HTR3E) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin for the detection of Human HTR3E.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | 5-hydroxytryptamine receptor 3E (HTR3E) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by antigen affinity chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Size 3 | 200 µl |
| Size 4 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | A5X5Y0 |
| Gene ID | 285242 |
| OMIM | 610123 |
| Alias | HTR3E,5-HT3E,5-HT3-E,5-HT3c1,5-HT3E receptor |
| Background | Antibody anti-HTR3E |
| Status | RUO |
Descripción
HTR3E is a member of the 5-HT3 receptor family, which functions as a ligand-gated ion channel receptor. HTR3E does not form functional channels on its own but combines with HTR3A to create heteromeric receptors that fine-tune serotonin's effects on neuronal excitation. Expressed primarily in the central nervous system and gastrointestinal tract, HTR3E contributes to the modulation of emetic responses, pain signaling, and gastrointestinal motility. Its presence alters the receptor's biophysical properties, including ion conductance and pharmacological sensitivity. HTR3E polymorphisms have been associated with functional gastrointestinal disorders, such as irritable bowel syndrome (IBS), by influencing visceral hypersensitivity and serotonin-mediated gut motility. Additionally, the HTR3E subunit plays a role in chemotherapy-induced nausea and vomiting (CINV) and serves as a target for 5-HT3 antagonists like ondansetron. The interaction of HTR3E with other subunits further increases the diversity of 5-HT3 receptor functions, making it a key modulator in serotonergic neurotransmission.
Related Products
5-hydroxytryptamine receptor 3E (HTR3E) Antibody
5-hydroxytryptamine receptor 3E (HTR3E) Antibody is a Rabbit Polyclonal antibody for the detection of Human HTR3E.
Ver Producto5-hydroxytryptamine receptor 3E (HTR3E) Antibody (HRP)
5-hydroxytryptamine receptor 3E (HTR3E) Antibody (HRP) is a Rabbit Polyclonal antibody conjugated to HRP for the detection of Human HTR3E.
Ver Producto
5-hydroxytryptamine receptor 3E (HTR3E) Antibody (FITC)
5-hydroxytryptamine receptor 3E (HTR3E) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC for the detection of Human HTR3E.
Ver Producto