5'-3' Exoribonuclease 2 (XRN2) Antibody
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Description
XRN2 Antibody is a Mouse Monoclonal against XRN2.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | 5'-3' Exoribonuclease 2 (XRN2) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Purification | Purified from ascites by Protein G chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, containing 0.05% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9H0D6 |
| Gene ID | 22803 |
| OMIM | 608851 |
| Background | Antibody anti-XRN2 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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XRN2 antibody
Possesses 5'->3' exoribonuclease activity(By similarity). May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II(RNAp II) transcription termination R-loops formed by G-rich pause sites(PubMed:21700224).
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5'-3' Exoribonuclease 2 (XRN2) Antibody
XRN2 Antibody is a Rabbit Polyclonal antibody against XRN2.
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5'-3' Exoribonuclease 2 (XRN2) Antibody
XRN2 Antibody is a Mouse Monoclonal against XRN2.
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