4-Hydroxy-2-hexenal (BSA)
520€ (50 µg)
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935106861
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name
4-Hydroxy-2-hexenal (BSA)
category
Proteins and Peptides
provider
Abbexa
reference
abx675028
tested applications
ELISA, WB
Description
4-Hydroxy-2-hexenal (BSA) is a protein conjugated to BSA.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | 4-Hydroxy-2-hexenal (BSA) |
| Host | Synthetic |
| Purity | > 98% |
| Size 1 | 50 µg |
| Form | |
| Tested Applications | ELISA, WB |
| Buffer | PBS pH 7.4, 0.09% Sodium Azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at -20°C. |
| Dry Ice | No |
| Alias | TRANS-4-HYDROXY-2-HEXENAL |
| Background | Protein 4-HHE |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
4-Hydroxy-2-hexenal (4-HHE) is a highly reactive lipid peroxidation product derived from the oxidation of omega-3 polyunsaturated fatty acids (PUFAs), such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). It is a reactive aldehyde that can modify proteins, nucleic acids, and lipids through covalent binding, leading to cellular damage or signaling modulation. 4-HHE plays a dual role in biological systems: at low concentrations, it acts as a signaling molecule regulating cellular responses like antioxidant defense and apoptosis, while at high levels, it induces cytotoxicity and contributes to oxidative stress. Elevated 4-HHE levels are associated with pathological conditions, including neurodegenerative diseases, cardiovascular disorders, and inflammation. Its formation is a marker of oxidative stress and can disrupt cellular homeostasis by altering protein function and membrane integrity. Studies continue to explore its role in modulating redox signaling and as a potential biomarker for lipid peroxidation-related damage.
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