4-Hydroxy-2-hexenal Antibody

Este producto es parte de 4-Hydroxy-2-hexenal
4-Hydroxy-2-hexenal Antibody

Pida mas información

935106861

info@markelab.com

Precio

637.5€ (100 µg)

Antibody anti-4-HHE

proveedor

Abbexa

reference

abx445115

Tested Applications

ELISA, WB, IF/ICC, FCM, FACS

reactivity

General

status

RUO

clonality

Monoclonal

Descripción

4-Hydroxy-2-hexenal Antibody is a Mouse Monoclonal antibody against 4-Hydroxy-2-hexenal.


Background

4-Hydroxy-2-hexenal (4-HHE) is a highly reactive lipid peroxidation product derived from the oxidation of omega-3 polyunsaturated fatty acids (PUFAs), such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). It is a reactive aldehyde that can modify proteins, nucleic acids, and lipids through covalent binding, leading to cellular damage or signaling modulation. 4-HHE plays a dual role in biological systems: at low concentrations, it acts as a signaling molecule regulating cellular responses like antioxidant defense and apoptosis, while at high levels, it induces cytotoxicity and contributes to oxidative stress. Elevated 4-HHE levels are associated with pathological conditions, including neurodegenerative diseases, cardiovascular disorders, and inflammation. Its formation is a marker of oxidative stress and can disrupt cellular homeostasis by altering protein function and membrane integrity. Studies continue to explore its role in modulating redox signaling and as a potential biomarker for lipid peroxidation-related damage.

Características del producto

category

Primary Antibodies


clonality

Monoclonal


reactivity

General


immunogen target

4-Hydroxy-2-hexenal


host

Mouse


conjugation

Unconjugated


tested applications

ELISA, WB, IF/ICC, FCM, FACS


purification

Purified by Protein G.


buffer

PBS, pH 7.4, 50% glycerol, 0.09% sodium azide.


size 1

100 µg


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

4-HHE


dry ice

No


availability

Shipped within 5-12 working days.


alias

TRANS-4-HYDROXY-2-HEXENAL


note

This product is for research use only.


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