935106861
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Precio
637.5€ (100 µg)
4-Hydroxy-2-hexenal Antibody is a Mouse Monoclonal antibody against 4-Hydroxy-2-hexenal.
4-Hydroxy-2-hexenal (4-HHE) is a highly reactive lipid peroxidation product derived from the oxidation of omega-3 polyunsaturated fatty acids (PUFAs), such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). It is a reactive aldehyde that can modify proteins, nucleic acids, and lipids through covalent binding, leading to cellular damage or signaling modulation. 4-HHE plays a dual role in biological systems: at low concentrations, it acts as a signaling molecule regulating cellular responses like antioxidant defense and apoptosis, while at high levels, it induces cytotoxicity and contributes to oxidative stress. Elevated 4-HHE levels are associated with pathological conditions, including neurodegenerative diseases, cardiovascular disorders, and inflammation. Its formation is a marker of oxidative stress and can disrupt cellular homeostasis by altering protein function and membrane integrity. Studies continue to explore its role in modulating redox signaling and as a potential biomarker for lipid peroxidation-related damage.
Primary Antibodies
Monoclonal
General
4-Hydroxy-2-hexenal
Mouse
Unconjugated
ELISA, WB, IF/ICC, FCM, FACS
Purified by Protein G.
PBS, pH 7.4, 50% glycerol, 0.09% sodium azide.
100 µg
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
4-HHE
No
Shipped within 5-12 working days.
TRANS-4-HYDROXY-2-HEXENAL
This product is for research use only.
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