3(2),5-Bisphosphate Nucleotidase 1 (BPNT1) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: 3(2),5-Bisphosphate Nucleotidase 1 (BPNT1) Immunogen: KLH-conjugated synthetic peptide between 277-305 amino acids from the C-terminal region of human BPNT1. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 33.4 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O95861 |
| Background | Antibody anti-BPNT1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Related Products
BPNT1 antibody
Converts adenosine 3'-phosphate 5'-phosphosulfate(PAPS) to adenosine 5'-phosphosulfate(APS) and 3'(2')-phosphoadenosine 5'-phosphate(PAP) to AMP. Has 1000-fold lower activity towards inositol 1,4-bisphosphate(Ins(1,4)P2) and inositol 1,3,4-trisphosphate(Ins(1,3,4)P3), but does not hydrolyze Ins(1)P, Ins(3,4)P2, Ins(1,3,4,5)P4 or InsP6.
Ver Producto
Recombinant Human BPNT1
Ver Producto
3(2),5-Bisphosphate Nucleotidase 1 (BPNT1) Antibody
BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
Ver Producto