26S Proteasome Non-ATPase Regulatory Subunit 5 (PSMD5) Antibody

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Description
PSMD5 Antibody is a Rabbit Polyclonal Antibody against PSMD5. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a non-ATPase subunit of the 19S regulator base that functions as a chaperone protein during 26S proteasome assembly.
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Product specifications
Category | Primary Antibodies |
Immunogen Target | 26S Proteasome Non-ATPase Regulatory Subunit 5 (PSMD5) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by affinity chromatography. |
Size 1 | 60 µl |
Size 2 | 120 µl |
Size 3 | 200 µl |
Form | Liquid |
Tested Applications | IHC |
Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q16401 |
Gene ID | 5711 |
NCBI Accession | NP_001257356.1, NM_001270427.1, NP_005038.1, NM_005047.3 |
OMIM | 604452 |
Background | Antibody anti-PSMD5 |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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