26S Proteasome Non-ATPase Regulatory Subunit 4 (PSMD4) Antibody
195€ (20 µl)
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935106861
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name
26S Proteasome Non-ATPase Regulatory Subunit 4 (PSMD4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx000984
tested applications
ELISA, WB, IF/ICC, IP
Description
PSMD4 Antibody is a Rabbit Polyclonal antibody against PSMD4. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. Pseudogenes have been identified on chromosomes 10 and 21.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | 26S Proteasome Non-ATPase Regulatory Subunit 4 (PSMD4) |
| Host | Rabbit |
| Reactivity | Human, Rat |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC, IP |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P55036 |
| Gene ID | 5710 |
| NCBI Accession | NP_002801.1, NM_002810.2 |
| OMIM | 601648 |
| Background | Antibody anti-PSMD4 |
| Status | RUO |
| Note | Concentration: 3.25 mg/ml - |
Descripción
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