26S Proteasome Non-ATPase Regulatory Subunit 14 (PSMD14) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Proteasome (Prosome, Macropain) 26S Subunit, Non-Atpase, 14 Antibody is a Rabbit Polyclonal antibody against Proteasome (Prosome, Macropain) 26S Subunit, Non-Atpase, 14.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | 26S Proteasome Non-ATPase Regulatory Subunit 14 (PSMD14) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O00487 |
| Gene ID | 10213 |
| OMIM | 607173 |
| Background | Antibody anti-PSMD14 |
| Status | RUO |
Descripción
Related Products
PSMD14 antibody
Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. Plays a role in response to double-strand breaks(DSBs): acts as a regulator of non-homologous end joining(NHEJ) by cleaving 'Lys-63'-linked polyubiquitin, thereby promoting retention of JMJD2A/KDM4A on chromatin and restricting TP53BP1 accumulation. Also involved in homologous recombination repair by promoting RAD51 loading.
Ver Producto
26S Proteasome Non-ATPase Regulatory Subunit 14 (PSMD14) Antibody
PSMD14 is a component of the 26S proteasome, a multiprotein complex that degrades proteins targeted for destruction by the ubiquitin pathway (Spataro et al., 1997 [PubMed 9374539]).
Ver Producto
26S Proteasome Non-ATPase Regulatory Subunit 14 (PSMD14) Antibody
Proteasome (Prosome, Macropain) 26S Subunit, Non-Atpase, 14 Antibody is a Rabbit Polyclonal antibody against Proteasome (Prosome, Macropain) 26S Subunit, Non-Atpase, 14.
Ver Producto