24-Dehydrocholesterol Reductase (DHCR24) Antibody

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Description
24-Dehydrocholesterol Reductase Antibody is a Rabbit Polyclonal antibody against 24-Dehydrocholesterol Reductase.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | 24-Dehydrocholesterol Reductase (DHCR24) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Antigen Affinity Chromatography. |
Size 1 | 100 µl |
Form | Liquid |
Tested Applications | ELISA, WB, IHC |
Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q15392 |
Gene ID | 1718 |
NCBI Accession | NP_055577.1, NM_014762.3 |
OMIM | 602398 |
Background | Antibody anti-DHCR24 |
Status | RUO |
Descripción
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DHCR24 antibody
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24-Dehydrocholesterol Reductase (DHCR24) Antibody
DHCR24 Antibody is a Rabbit Polyclonal antibody against DHCR24. This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
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24-Dehydrocholesterol Reductase (DHCR24) Antibody
DHCR24 is a flavin adenine dinucleotide (FAD) dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. This protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of its gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
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