2'-5'-Oligoadenylate Synthetase 3 (OAS3) Antibody

2'-5'-Oligoadenylate Synthetase 3 (OAS3) Antibody
292.5€ (80 µl)

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Name
2'-5'-Oligoadenylate Synthetase 3 (OAS3) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx032743
Tested Applications
ELISA, WB

Description

OAS3 is an interferon inducible protein that belongs to the 2-5A synthetase family, may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. OAS3 synthesizes preferentially dimeric 2', 5'-oligoadenylate molecules. GTP can be an alternative substrate. OAS3 binds double-stranded RNA and polymerizes ATP into PPP (A2'P5'A) N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. The protein is present at high level in placenta trophoblast.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: 2'-5'-Oligoadenylate Synthetase 3 (OAS3)
Immunogen: KLH-conjugated synthetic peptide between 1056-1087 amino acids from the C-terminal region of human OAS3.
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Calculated MW: 121 kDa
Purification
Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Size 1
80 µl
Size 2
400 µl
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS containing 0.09% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9Y6K5
Background
Antibody anti-OAS3
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

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