2'-5'-Oligoadenylate Synthase-Like Protein (OASL) Antibody

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Description
OASL Antibody is a Rabbit Polyclonal against OASL.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | 2'-5'-Oligoadenylate Synthase-Like Protein (OASL) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | ELISA: 1 µg/ml, WB: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by affinity chromatography. |
Size 1 | 20 µl |
Size 2 | 100 µl |
Size 3 | 2 × 100 µl |
Form | Liquid |
Tested Applications | ELISA, WB |
Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q15646 |
Gene ID | 8638 |
NCBI Accession | NP_003724.1 |
OMIM | 603281 |
Background | Antibody anti-OASL |
Status | RUO |
Note | Concentration: > 0.2 mg/ml - |
Descripción
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2'-5'-Oligoadenylate Synthase-Like Protein (OASL) Antibody
2-prime, 5-prime oligoadenylates (2-5As) bind to and activate RNase L, leading to degradation of RNA and inhibition of protein synthesis. 2-5As are produced by 2-5A synthetases (OASs), a highly-conserved family of interferon-induced enzymes. The predicted 514-amino acid human p59OASL (2-5A synthetases-like) protein shares a highly conserved N-terminal domain with other OASs. The C-terminal portion of p59OASL contains 2 ubiquitin-like domains. p59OASL is expressed in most tissues, with the highest levels in hematopoietic tissues, colon, and stomach.
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