11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11B1) Antibody
195€ (20 µl)
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935106861
info@markelab.com
name
11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11B1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx001363
tested applications
ELISA, WB
Description
HSD11B1 Antibody is a Rabbit Polyclonal antibody against HSD11B1. The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | 11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11B1) |
| Host | Rabbit |
| Reactivity | Mouse |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P28845 |
| Gene ID | 3290 |
| NCBI Accession | NP_005516.1 |
| Background | Antibody anti-HSD11B1 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
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