1-Acylglycerol-3-Phosphate O-Acyltransferase 5 (AGPAT5) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
1-Acylglycerol-3-Phosphate O-Acyltransferase 5 (AGPAT5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx030540
tested applications
ELISA, WB
Description
This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | 1-Acylglycerol-3-Phosphate O-Acyltransferase 5 (AGPAT5) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NUQ2 |
| Alias | 1AGPAT5,LPAATE,LPLAT5 |
| Background | Antibody anti-AGPAT5 |
| Status | RUO |
Descripción
AGPAT5 catalyzes the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA), a precursor for the synthesis of glycerophospholipids and triglycerides. AGPAT5 is highly expressed in adipose tissue, liver, and muscle, playing a critical role in lipid storage, membrane formation, and cell signaling pathways. It is particularly important in regulating adipogenesis and energy homeostasis. Studies suggest that AGPAT5 may influence the composition of lipid droplets and contribute to metabolic flexibility. Dysregulation of AGPAT5 has been associated with insulin resistance, obesity, and non-alcoholic fatty liver disease (NAFLD), emphasizing its significance in lipid metabolism and metabolic health. Further investigations are needed to clarify its contributions to lipid-related disorders.
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