Family main features
HEPACAM family member 2, often referred to as HEPACAM2, is a protein encoded by the HEPACAM2 gene in humans. This protein belongs to the HEPACAM (Heparan sulfate proteoglycan 2) family, which includes cell adhesion molecules that play significant roles in cellular processes such as proliferation, differentiation, and migration. HEPACAM2 is widely expressed in various tissues, indicating its importance in multiple biological functions. The HEPACAM family proteins are known for their roles in modulating cell-cell and cell-matrix interactions, contributing to the maintenance of tissue integrity and function.
The structure of HEPACAM2 is characterized by several distinct domains:
The precise conformation of these domains allows HEPACAM2 to function effectively in cellular adhesion and signaling processes.
HEPACAM2 is part of the HEPACAM family, which also includes HEPACAM1 and other related proteins. These proteins share structural similarities, particularly in their Ig-like domains and transmembrane regions. However, each member of the family has distinct expression patterns and functions, reflecting their specialized roles in different tissues and cellular contexts.
HEPACAM2 plays several vital roles in cellular processes:
Alterations in the expression or function of HEPACAM2 are associated with several clinical conditions:
HEPACAM2 is a vital cell adhesion molecule within the HEPACAM family, playing essential roles in maintaining tissue integrity, regulating cell signaling, and controlling cell migration. Its structure, characterized by Ig-like domains, heparan sulfate binding sites, a transmembrane domain, and a cytoplasmic tail, enables these functions. HEPACAM2's involvement in critical biological processes highlights its importance in health and disease. Clinical issues related to HEPACAM2 include cancer, neurological disorders, inflammatory diseases, and fibrotic conditions. Understanding the molecular mechanisms of HEPACAM2 function and its role in various diseases could lead to novel therapeutic approaches for these conditions.
HEPACAM family member 2
MIKI,Mitotic kinetics regulator
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, Primary Antibodies, ELISA Kits) relacionados con HEPACAM family member 2
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Esta página contiene 7 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | HEPACAM2 | abx385001 | Human HEPACAM Family Member 2 (HEPACAM2) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.07 ng/ml | 687.5 | 96 tests | A8MVW5 | RUO |
Abbexa | HEPACAM2 | abx389526 | Mouse HEPACAM Family Member 2 (HEPACAM2) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.07 ng/ml | 687.5 | 96 tests | Q4VAH7 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | HEPACAM2 | abx304135 | HEPACAM Family Member 2 (HEPACAM2) Antibody | Human | Polyclonal | Rabbit | HEPACAM Family Member 2 (HEPACAM2) | Unconjugated | ELISA, IHC | 162.5 | 20 µg | A8MVW5 | RUO | |
Abbexa | HEPACAM2 | abx145592 | HEPACAM Family Member 2 (HEPACAM2) Antibody | Human | Polyclonal | Rabbit | HEPACAM Family Member 2 (HEPACAM2) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | A8MVW5 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | HEPACAM2 | abx262689 | HEPACAM2 Protein | Recombinant | Unconjugated | SDS-PAGE | 225 | 2 µg | A8MVW5 | RUO | ||
Abbexa | HEPACAM2 | abx690874 | Rat HEPACAM Family Member 2 (HEPACAM2) Protein | Rat | Recombinant | HEK293 cells | SDS-PAGE | 962.5 | 100 µg | RUO | ||
Abbexa | HEPACAM2 | abx691462 | Rat HEPACAM Family Member 2 (HEPACAM2) Protein | Rat | Recombinant | HEK293 cells | SDS-PAGE | 962.5 | 100 µg | RUO |
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