Family main features
CD300LG, also known as CD300 molecule-like family member G, is a protein encoded by the CD300LG gene located on chromosome 17 in humans. It belongs to the CD300 family of molecules, which are a subset of the immunoglobulin (Ig) superfamily. These proteins play significant roles in the immune system, particularly in regulating cell adhesion and immune responses. CD300LG is primarily expressed on endothelial cells lining blood vessels and is involved in leukocyte trafficking, which is critical for immune surveillance and response to inflammation.
CD300LG is a type I transmembrane glycoprotein characterized by several key structural components:
CD300LG is a member of the CD300 family, which is divided into activating and inhibitory receptors based on their cytoplasmic signaling motifs. The CD300 family includes various molecules such as CD300A, CD300B, CD300C, CD300D, CD300E, CD300F, and CD300G. These proteins have diverse roles in immune regulation, with some functioning primarily as activating receptors (containing ITAMs - immunoreceptor tyrosine-based activation motifs) and others as inhibitory receptors (containing ITIMs - immunoreceptor tyrosine-based inhibitory motifs).
CD300LG has several important functions in the immune system:
The functions of CD300LG in immune regulation have significant implications for various clinical conditions:
CD300LG, a member of the CD300 family, is a type I transmembrane glycoprotein that plays a crucial role in immune regulation, particularly in leukocyte adhesion and trafficking. Its structure includes an extracellular Ig-like domain, a transmembrane region, and a cytoplasmic tail with signaling motifs. CD300LG facilitates the migration of leukocytes to sites of inflammation, aiding in immune surveillance and the regulation of inflammatory responses. Dysregulation of CD300LG is implicated in various clinical conditions, including inflammatory diseases, autoimmune disorders, infectious diseases, and cancer. Understanding the molecular mechanisms and clinical implications of CD300LG is essential for developing therapeutic strategies aimed at modulating immune responses in these conditions.
CD300 molecule like family member g (CD300LG)
CLM9,TREM4,CD300 antigen-like family member G,Triggering receptor expressed on myeloid cells 4,CMRF35-like molecule 9
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, ELISA Kits, Primary Antibodies) relacionados con CD300LG molecule like family member g
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Esta página contiene 15 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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FineTest | CD300LG | EH7189 | Human CD300LG (CMRF35-like molecule 9) ELISA Kit | human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 0.313-20ng/ml | 96T | Q6UXG3 | RUO | ||
Abbexa | CD300LG | abx386393 | Human CMRF35-Like Molecule 9 / TREM4 (CD300LG) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.313 ng/ml - 20 ng/ml | < 0.19 ng/ml | 687.5 | 96 tests | Q6UXG3 | RUO |
Abbexa | CD300LG | abx390789 | Mouse CMRF35-Like Molecule 9 / TREM4 (CD300LG) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | 687.5 | 96 tests | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | CD300LG | FNab01462 | anti- CD300LG antibody | human | polyclonal | Rabbit | CD300 molecule-like family member g | IgG | Unconjugated | ELISA, WB | 100µg | Q6UXG3 | RUO | |
Abbexa | CD300LG | abx231462 | CMRF35-Like Molecule 9 / TREM4 (CD300LG) Antibody | Human | Polyclonal | Rabbit | CMRF35-Like Molecule 9 / TREM4 (CD300LG) | Unconjugated | ELISA, WB | 350 | 100 µg | Q6UXG3 | RUO | |
Abbexa | CD300LG | abx146179 | CMRF35-Like Molecule 9 / TREM4 (CD300LG) Antibody | Human | Polyclonal | Rabbit | CMRF35-Like Molecule 9 / TREM4 (CD300LG) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | RUO | ||
Abbexa | CD300LG | abx323654 | CMRF35-Like Molecule 9 / TREM4 (CD300LG) Antibody | Human | Polyclonal | Rabbit | CMRF35-Like Molecule 9 / TREM4 (CD300LG) | Unconjugated | ELISA, WB | 187.5 | 50 µg | Q6UXG3 | RUO | |
Abbexa | CD300LG | abx335140 | CMRF35-Like Molecule 9 / TREM4 (CD300LG) Antibody (FITC) | Human | Polyclonal | Rabbit | CMRF35-Like Molecule 9 / TREM4 (CD300LG) | FITC | 162.5 | 20 µg | Q6UXG3 | RUO | ||
Abbexa | CD300LG | abx335141 | CMRF35-Like Molecule 9 / TREM4 (CD300LG) Antibody (Biotin) | Human | Polyclonal | Rabbit | CMRF35-Like Molecule 9 / TREM4 (CD300LG) | Biotin | ELISA | 162.5 | 20 µg | Q6UXG3 | RUO | |
Abbexa | CD300LG | abx335139 | CMRF35-Like Molecule 9 / TREM4 (CD300LG) Antibody (HRP) | Human | Polyclonal | Rabbit | CMRF35-Like Molecule 9 / TREM4 (CD300LG) | HRP | ELISA | 162.5 | 20 µg | Q6UXG3 | RUO | |
Abbexa | CD300LG | abx111475 | CMRF35-Like Molecule 9 / TREM4 (CD300LG) Antibody | Human | Polyclonal | Rabbit | CMRF35-Like Molecule 9 / TREM4 (CD300LG) | Unconjugated | ELISA, WB | 612.5 | 100 µl | Q6UXG3 | RUO | |
Abbexa | CD300LG | abx338662 | CMRF35-Like Molecule 9 / TREM4 (CD300LG) Antibody | Human | Polyclonal | Rabbit | CMRF35-Like Molecule 9 / TREM4 (CD300LG) | Unconjugated | ELISA, WB, IHC, IF/ICC | 162.5 | 20 µg | Q6UXG3 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | CD300LG | abx692587 | Rat CMRF35-Like Molecule 9 (CD300LG) Protein | Rat | Recombinant | HEK293 cells | SDS-PAGE | 962.5 | 100 µg | RUO | ||
Abbexa | CD300LG | abx693712 | Human CMRF35-Like Molecule 9 / TREM4 (CD300LG) Protein | Human | Recombinant | HEK293 cells | SDS-PAGE | 962.5 | 100 µg | RUO | ||
Abbexa | CD300LG | abx691430 | Human CMRF35-Like Molecule 9 / TREM4 (CD300LG) Protein | Human | Recombinant | HEK293 cells | SDS-PAGE | 487.5 | 50 µg | RUO |
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