Family main features
CD300LF, also known as CD300 molecule-like family member F, is a receptor protein encoded by the CD300LF gene located on chromosome 17. This protein is part of the immunoglobulin (Ig) superfamily and is predominantly expressed on myeloid cells, including dendritic cells, macrophages, and some subsets of lymphocytes. CD300LF is characterized by its role in regulating immune responses through inhibitory signaling pathways, distinguishing it from other members of the CD300 family that may have activating functions.
CD300LF is a type I transmembrane glycoprotein with the following key structural components:
CD300LF belongs to the CD300 family, which is divided into activating and inhibitory receptors based on their cytoplasmic signaling motifs. CD300LF is classified as an inhibitory receptor due to its ITIM motif. Other members of the CD300 family include:
CD300LF plays a pivotal role in modulating immune responses through its inhibitory functions:
The role of CD300LF in immune regulation has significant implications for various clinical conditions:
CD300LF, a member of the CD300 family, serves as an inhibitory receptor primarily expressed on myeloid cells. Its structure features an extracellular Ig-like domain, a transmembrane region, and a cytoplasmic tail with an ITIM motif. CD300LF plays a crucial role in regulating immune responses, particularly by inhibiting excessive activation of immune cells. It interacts with ligands such as phosphatidylserine, facilitating the clearance of apoptotic cells and maintaining immune homeostasis. Dysregulation of CD300LF is implicated in various clinical conditions, including autoimmune diseases, chronic inflammatory disorders, infectious diseases, and cancer. Understanding the molecular mechanisms and clinical implications of CD300LF is essential for developing therapeutic strategies aimed at modulating immune responses in these conditions.
CD300 molecule like family member f (CD300LF)
CD300F,CLM1,IGSF13,IREM1,NKIR,CD300 antigen-like family member F,Immune receptor expressed on myeloid cells 1,Immunoglobulin superfamily member 13,NK inhibitory receptor
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, Primary Antibodies, ELISA Kits) relacionados con CD300LF molecule like family member f
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 12 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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Abbexa | CD300LF | abx386392 | Human CMRF35-Like Molecule 1 / IREM1 (CD300LF) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.094 ng/ml | 687.5 | 96 tests | Q8TDQ1 | RUO |
Abbexa | CD300LF | abx389594 | Mouse CMRF35-Like Molecule 1 / IREM1 (CD300LF) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.094 ng/ml | 687.5 | 96 tests | Q6SJQ7 | RUO |
Abbexa | CD300LF | abx391479 | Rat CMRF35-Like Molecule 1 / IREM1 (CD300LF) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.094 ng/ml | 687.5 | 96 tests | Q566E6 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | CD300LF | FNab01461 | anti- CD300LF antibody | human | polyclonal | Rabbit | CD300 molecule-like family member f | IgG | Unconjugated | ELISA, WB | 100µg | Q8TDQ1 | RUO | |
Abbexa | CD300LF | abx231461 | CMRF35-Like Molecule 1 / IREM1 (CD300LF) Antibody | Human | Polyclonal | Rabbit | CMRF35-Like Molecule 1 / IREM1 (CD300LF) | Unconjugated | ELISA, WB | 350 | 100 µg | Q8TDQ1 | RUO | |
Abbexa | CD300LF | abx308810 | CMRF35-Like Molecule 1 / IREM1 (CD300LF) Antibody (FITC) | Human | Polyclonal | Rabbit | CMRF35-Like Molecule 1 / IREM1 (CD300LF) | FITC | 162.5 | 20 µg | Q8TDQ1 | RUO | ||
Abbexa | CD300LF | abx301504 | CMRF35-Like Molecule 1 / IREM1 (CD300LF) Antibody | Human | Polyclonal | Rabbit | CMRF35-Like Molecule 1 / IREM1 (CD300LF) | Unconjugated | ELISA, IHC | 162.5 | 20 µg | Q8TDQ1 | RUO | |
Abbexa | CD300LF | abx323906 | CMRF35-Like Molecule 1 / IREM1 (CD300LF) Antibody | Human | Polyclonal | Rabbit | CMRF35-Like Molecule 1 / IREM1 (CD300LF) | Unconjugated | ELISA, WB | 187.5 | 50 µg | Q8TDQ1 | RUO | |
Abbexa | CD300LF | abx308811 | CMRF35-Like Molecule 1 / IREM1 (CD300LF) Antibody (Biotin) | Human | Polyclonal | Rabbit | CMRF35-Like Molecule 1 / IREM1 (CD300LF) | Biotin | ELISA | 162.5 | 20 µg | Q8TDQ1 | RUO | |
Abbexa | CD300LF | abx308809 | CMRF35-Like Molecule 1 / IREM1 (CD300LF) Antibody (HRP) | Human | Polyclonal | Rabbit | CMRF35-Like Molecule 1 / IREM1 (CD300LF) | HRP | ELISA | 162.5 | 20 µg | Q8TDQ1 | RUO | |
Abbexa | CD300LF | abx323653 | CMRF35-Like Molecule 1 / IREM1 (CD300LF) Antibody | Human | Polyclonal | Rabbit | CMRF35-Like Molecule 1 / IREM1 (CD300LF) | Unconjugated | ELISA, WB | 187.5 | 50 µg | Q8TDQ1 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | CD300LF | P1962 | Recombinant Human CD300LF | Human | Recombinant | E.Coli | Western Blot, ELISA | 50μg | Q8TDQ1 | RUO |
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