Family main features
Acrosin Binding Protein (ACRBP), also known as sp32, is a protein found in the acrosome of sperm cells. It plays a significant role in the regulation and stabilization of acrosin, a crucial enzyme for the fertilization process. ACRBP is essential for proper acrosome function and sperm-oocyte interaction.The acrosome is a specialized structure located at the tip of the sperm head, containing enzymes like acrosin that are essential for sperm penetration through the protective layers surrounding the egg during fertilization. This protein is located in the sperm acrosome and is thought to function as a binding protein to proacrosin for packaging and condensation of the acrosin zymogen in the acrosomal matrix.
The structure of ACRBP includes several key features:
ACRBP does not have multiple subtypes but exists in different forms depending on its interaction state with acrosin:
ACRBP serves several important functions in the reproductive process:
ACRBP interacts with various molecules and structures during fertilization:
Dysfunction or deficiency in ACRBP can have significant implications for fertility:
Acrosin Binding Protein (ACRBP) is a crucial protein in the acrosome of sperm cells, playing a key role in stabilizing and regulating acrosin, an enzyme essential for fertilization. By binding to proacrosin, ACRBP maintains the enzyme in an inactive state until it is needed, ensuring proper timing of acrosin release during the acrosome reaction. ACRBP's interactions with proacrosin/acrosin and other acrosomal proteins are vital for sperm penetration of the oocyte’s zona pellucida. Dysregulation of ACRBP can lead to male infertility and fertilization failures, highlighting its importance in reproductive health and potential as a diagnostic marker for fertility assessment.
Acrosin Binding Protein(ACRBP)
CT23,OY-TES-1,SP32
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Primary Antibodies, ELISA Kits) relacionados con ACRBP - Acrosin Binding Protein
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Esta página contiene 7 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | ACRBP | EH13917 | Human ACRBP (Acrosin-binding protein) ELISA Kit | human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 78.125-5000pg/ml | 96T | Q8NEB7 | RUO | ||
Abbexa | ACRBP | abx384539 | Human Acrosin Binding Protein (ACRBP) ELISA Kit | Human | Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.094 ng/ml | 687.5 | 96 tests | Q8NEB7 | RUO |
Abbexa | ACRBP | abx388490 | Mouse Acrosin Binding Protein (ACRBP) ELISA Kit | Mouse | Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.094 ng/ml | 687.5 | 96 tests | Q3V140 | RUO |
Abbexa | ACRBP | abx390920 | Rat Acrosin Binding Protein (ACRBP) ELISA Kit | Rat | Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.094 ng/ml | 687.5 | 96 tests | Q6AY33 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | ACRBP | abx037577 | Acrosin Binding Protein (ACRBP) Antibody | Human | Polyclonal | Rabbit | Acrosin Binding Protein (ACRBP) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | RUO | ||
Abbexa | ACRBP | abx324805 | Acrosin Binding Protein (ACRBP) Antibody | Human | Polyclonal | Rabbit | Acrosin Binding Protein (ACRBP) | Unconjugated | ELISA, WB, IHC, IF/ICC | 187.5 | 50 µg | Q8NEB7 | RUO | |
Abbexa | ACRBP | abx013699 | Acrosin Binding Protein (ACRBP) Antibody | Human | Polyclonal | Rabbit | Acrosin Binding Protein (ACRBP) | Unconjugated | ELISA, WB | 43.75 | 10 µg | Q8NEB7 | RUO |
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