Zona pellucida sperm-binding protein 4 (ZP4) Antibody (Biotin)
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Description
Zona pellucida sperm-binding protein 4 (ZP4) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin for the detection of Human ZP4.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Zona pellucida sperm-binding protein 4 (ZP4) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q12836 |
| Gene ID | 57829 |
| OMIM | 613514 |
| Background | Antibody anti-ZP4 |
| Status | RUO |
Descripción
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The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo protein composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain protein hypothesized that furin cleavage results in release of the mature the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4.
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