Zinc Finger Protein Neuro-D4 (DPF1) Antibody
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Description
DPF1 Antibody is a Rabbit Polyclonal against DPF1.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Zinc Finger Protein Neuro-D4 (DPF1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 20 µl |
| Size 2 | 50 µl |
| Size 3 | 100 µl |
| Size 4 | 200 µl |
| Size 5 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q92782 |
| Gene ID | 8193 |
| NCBI Accession | NP_001128627.1, NM_001135155.2, NP_001128628.1, NM_001135156.2, NP_001276907.1, NM_001289978.1, NP_004638.2, NM_004647.3 |
| OMIM | 601670 |
| Background | Antibody anti-DPF1 |
| Status | RUO |
Descripción
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Zinc Finger Protein Neuro-D4 (DPF1) Antibody
DPF1 Antibody is a Rabbit Polyclonal Antibody against DPF1.
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Zinc Finger Protein Neuro-D4 (DPF1) Antibody
DPF1 may have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).
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