Zinc Finger E-Box-Binding Homeobox 1 (ZEB1) Antibody
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Description
Zinc Finger E-Box-Binding Homeobox 1 (ZEB1) Antibody is a Rabbit polyclonal antibody for the detection of Human Zinc Finger E-Box-Binding Homeobox 1 (ZEB1).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Zinc Finger E-Box-Binding Homeobox 1 (ZEB1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8 °C for up to 2 weeks. For long-term storage, aliquot and store at -80 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P37275 |
| Gene ID | 6935 |
| NCBI Accession | NP_001121600.1 |
| Background | Antibody anti-ZEB1 |
| Status | RUO |
Descripción
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Human ZEB1 (Zinc finger E-box-binding homeobox 1) ELISA Kit
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ZEB1 antibody
Acts as a transcriptional repressor. Inhibits interleukin-2(IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition(EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box(5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs. The calculated molecular weight of ZEB1 is 124 kDa, but the post phosphorylation of protein is about 190-210 kDa. This is a rabbit polyclonal antibody raised against part of the full length of ZEB1 of human.
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