YTH Domain Family Protein 2 (YTHDF2) Antibody (Biotin)

Product Graph
169€ (20 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
YTH Domain Family Protein 2 (YTHDF2) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx312442
tested applications
ELISA

Description

YTHDF2 Antibody (Biotin) is a Rabbit Polyclonal against YTHDF2 conjugated to Biotin.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
YTH Domain Family Protein 2 (YTHDF2)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Biotin
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9Y5A9
Gene ID
51441
NCBI Accession
NP_001166299.1, NM_001172828.1, NP_001166599.1, NM_001173128.1
OMIM
610640
Background
Antibody anti-YTHDF2
Status
RUO

Descripción

Related Products

FNab09573

YTHDF2 antibody

Specifically recognizes and binds N6-methyladenosine(m6A)-containing RNAs, and regulates mRNA stability(PubMed:24284625, PubMed:26046440, PubMed:26318451). M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability(PubMed:22575960, PubMed:24284625, PubMed:25412658, PubMed:25412661). Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in the localization to mRNA decay sites, such as processing bodies(P-bodies), leading to mRNA degradation(PubMed:24284625, PubMed:26046440). Also acts as a promoter of cap-independent mRNA translation following heat shock stress: upon stress, relocalizes to the nucleus and specifically binds mRNAs with some m6A methylation mark at their 5'-UTR, protecting demethylation of mRNAs by FTO, thereby promoting cap-independent mRNA translation(PubMed:26458103).

Ver Producto
P1982

Recombinant Human YTHDF2

Ver Producto
abx036130

YTH Domain Family Protein 2 (YTHDF2) Antibody

Rabbit Polyclonal against the YTHDF2 protein.

Ver Producto