X-Ray Repair Cross Complementing 3 (XRCC3) Antibody
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Description
XRCC3 Antibody is a Rabbit Polyclonal antibody against XRCC3. This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damageThis gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstableA rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivityAlternatively spliced transcript variants encoding the same protein have been identified[provided by RefSeq, Jul 2008]This protein is involved in Epigenetics and Nuclear Signaling.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | X-Ray Repair Cross Complementing 3 (XRCC3) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O43542 |
| Gene ID | 7517 |
| Background | Antibody anti-XRCC3 |
| Status | RUO |
Descripción
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X-Ray Repair Cross Complementing 3 (XRCC3) Antibody
XRCC3 Antibody is a Rabbit Polyclonal antibody against XRCC3. This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008].
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