WD repeat and FYVE domain-containing protein 3 (WDFY3) Antibody (FITC)
169€ (20 µg)
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Name
WD repeat and FYVE domain-containing protein 3 (WDFY3) Antibody (FITC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx338303
Description
WDFY3 Antibody (FITC) is a Rabbit Polyclonal against WDFY3.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: WD repeat and FYVE domain-containing protein 3 (WDFY3) Immunogen: Recombinant Human WD repeat and FYVE domain-containing protein 3 protein (1-100AA). |
| Host | Rabbit |
| Reactivity | Human |
| Detection Method | Laser Line: 488 Excitation/Emission: 499/515 |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8IZQ1 |
| Gene ID | 23001 |
| Alias | ALFY,BCHS,MCPH18,ZFYVE25,KIAA0993,Autophagy-linked FYVE protein (Alfy) |
| Background | Antibody anti-WDFY3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
WD repeat and FYVE domain containing 3 (WDFY3) is a protein that contains WD repeats and a FYVE domain, both of which are known for their roles in protein interactions and intracellular signaling. The WD repeats are typically involved in mediating interactions with other proteins, often forming large complexes that regulate various cellular processes. The FYVE domain in WDFY3 allows it to bind to phosphoinositides, specifically to the lipid molecules found in the membrane of endosomes and other intracellular vesicles. This interaction is crucial for the protein's role in vesicular trafficking and membrane dynamics, where it is involved in sorting and regulating endocytic cargo. Additionally, WDFY3 has been implicated in cellular processes such as autophagy and immune responses, both of which are essential for maintaining cellular homeostasis and immunity. Dysregulation of WDFY3 has been associated with several disorders, particularly those affecting cellular transport and immune function. Understanding how WDFY3 functions within the endosomal network and its role in various signaling pathways is critical for the development of therapeutic strategies aimed at diseases involving vesicular trafficking and immune dysregulation.
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