WD Repeat And FYVE Domain-Containing Protein 3 (WDFY3) Antibody
442€ (200 µl)
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Name
WD Repeat And FYVE Domain-Containing Protein 3 (WDFY3) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx430167
Tested Applications
P-ELISA, WB
Description
WDFY3 Antibody is a Goat Polyclonal antibody against WDFY3.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: WD Repeat And FYVE Domain-Containing Protein 3 (WDFY3) Immunogen: abx617246 - Internal region: C-SPERSTRTQQKEFQT |
| Host | Goat |
| Reactivity | Mouse |
| Assay Type | Concentration: 0.5 mg/ml |
| Recommended Dilution | P-ELISA: 1/128000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, WB |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 23001, 72145, 305164 |
| NCBI Accession | NP_055806.2 |
| Alias | ALFY,BCHS,MCPH18,ZFYVE25,KIAA0993,Autophagy-linked FYVE protein (Alfy) |
| Background | Antibody anti-WDFY3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
WD repeat and FYVE domain containing 3 (WDFY3) is a protein that contains WD repeats and a FYVE domain, both of which are known for their roles in protein interactions and intracellular signaling. The WD repeats are typically involved in mediating interactions with other proteins, often forming large complexes that regulate various cellular processes. The FYVE domain in WDFY3 allows it to bind to phosphoinositides, specifically to the lipid molecules found in the membrane of endosomes and other intracellular vesicles. This interaction is crucial for the protein's role in vesicular trafficking and membrane dynamics, where it is involved in sorting and regulating endocytic cargo. Additionally, WDFY3 has been implicated in cellular processes such as autophagy and immune responses, both of which are essential for maintaining cellular homeostasis and immunity. Dysregulation of WDFY3 has been associated with several disorders, particularly those affecting cellular transport and immune function. Understanding how WDFY3 functions within the endosomal network and its role in various signaling pathways is critical for the development of therapeutic strategies aimed at diseases involving vesicular trafficking and immune dysregulation.
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