Villin 1 (VIL1) Antibody

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Description
VIL1 Antibody is a Mouse Monoclonal against VIL1.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | Villin 1 (VIL1) |
Host | Mouse |
Reactivity | Human |
Recommended Dilution | ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Monoclonal |
Isotype | IgG2b |
Purification | Purified from ascites by Protein G chromatography. |
Size 1 | 100 µl |
Form | Liquid |
Tested Applications | ELISA, IHC |
Buffer | PBS, containing 0.05% sodium azide. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P09327 |
Gene ID | 7429 |
OMIM | 193040 |
Background | Antibody anti-VIL1 |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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VIL1 antibody
Villin 1(VIL1) is a 95-kd F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border, like epithelial cells of the intestinal mucosa, gall bladder, renal proximal tubules and ductuli efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein, and to have an important function in regulating actin dynamics, cell morphology, epithelial-to-mesenchymal transitions, cell migration and cell survival. In addition, VIL1 is a useful diagnostic marker for of various cancer, like cervical and endometrial adenocarcinomas, renal cell carcinoma. VIL1 was recently identified as a novel biomarker predictive for postoperative recurrence and poorer prognosis of high serum AFP associated HCC.
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VIL1 antibody
Villin 1(VIL1) is a 95-kd F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border, like epithelial cells of the intestinal mucosa, gall bladder, renal proximal tubules and ductuli efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein, and to have an important function in regulating actin dynamics, cell morphology, epithelial-to-mesenchymal transitions, cell migration and cell survival. In addition, VIL1 is a useful diagnostic marker for of various cancer, like cervical and endometrial adenocarcinomas, renal cell carcinoma. VIL1 was recently identified as a novel biomarker predictive for postoperative recurrence and poorer prognosis of high serum AFP associated HCC.
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