Vesicle-Associated Membrane Protein 8 (VAMP8) Antibody
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Description
Vesicle-Associated Membrane Protein 8 (VAMP8) Antibody is a Rabbit polyclonal antibody for the detection of Human Vesicle-Associated Membrane Protein 8 (VAMP8).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Vesicle-Associated Membrane Protein 8 (VAMP8) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BV40 |
| Gene ID | 8673 |
| NCBI Accession | NP_003752.2 |
| Background | Antibody anti-VAMP8 |
| Status | RUO |
Descripción
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VAMP8 antibody
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex(PubMed:23217709, PubMed:25686604). Also required for dense-granule secretion in platelets(PubMed:12130530). Plays also a role in regulated enzyme secretion in pancreatic acinar cells(By similarity). Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells(By similarity). Involved in the homotypic fusion of early and late endosomes(By similarity).
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Vesicle-Associated Membrane Protein 8 (VAMP8) Antibody
Involved in the targeting and/or fusion of transport vesicles to their target membrane. Involved for dense-granule secretion in platelets. Plays a role in regulated enzyme secretion in pancreatic acinar cells. Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. Involved in the homotypic fusion of early and late endosomes (By similarity).
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Vesicle-Associated Membrane Protein 8 (VAMP8) Antibody
VAMP8 Antibody is a Rabbit Polyclonal against VAMP8.
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