VDR (pS208) Antibody
429€ (100 µl)
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935106861
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name
VDR (pS208) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx332911
tested applications
ELISA, WB
Description
VDR (pS208) Antibody is a Rabbit Polyclonal against VDR (pS208).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | VDR (pS208) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS (without Mg2+ and Ca2+), pH 7.4, containing 150mM NaCl, 0.02% sodium azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P11473 |
| Alias | NR1I1,PPP1R163,Vitamin D3 receptor,1,25-dihydroxyvitamin D3 receptor,Nuclear receptor subfamily 1 group I member 1 |
| Background | Antibody anti-VDR |
| Status | RUO |
Descripción
Vitamin D receptor (VDR) is a nuclear receptor that mediates the effects of vitamin D, a crucial nutrient involved in calcium and phosphate homeostasis, bone health, immune function, and cellular growth VDR is activated upon binding to the active form of vitamin D, calcitriol, which allows it to regulate gene expression by binding to vitamin D response elements (VDREs) in target genes VDR is involved in regulating calcium absorption in the intestine, bone mineralization, and the modulation of immune responses, particularly in regulating inflammation and the function of T cells It also plays a role in the prevention of certain cancers, cardiovascular diseases, and autoimmune disorders Dysregulation of VDR activity has been linked to diseases such as osteoporosis, rickets, cardiovascular disease, and cancer In addition, VDR is a target for therapies aimed at managing conditions related to vitamin D deficiency, autoimmune diseases, and bone disorders
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