Vasopressin V1a Receptor (AVPR1A) Antibody
416€ (200 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Vasopressin V1a Receptor (AVPR1A) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx431978
tested applications
P-ELISA, WB
Description
AVPR1A Antibody is a Goat Polyclonal antibody against AVPR1A.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Vasopressin V1a Receptor (AVPR1A) |
| Host | Goat |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | P-ELISA: 1/64000, WB: 0.03-0.1 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, WB |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 552, 54140, 25107 |
| NCBI Accession | NP_000697.1 |
| Alias | AVPR1A,V1aR,AVPR1,antidiuretic hormone receptor 1a,AVPRAVPR V1a |
| Background | Antibody anti-AVPR1A |
| Status | RUO |
| Note | Concentration: 0.5 mg/ml - |
Descripción
AVPR1A is a G protein-coupled receptor that is activated by arginine vasopressin (AVP), a hormone involved in regulating water balance, blood pressure, and social behaviors. AVPR1A primarily couples to Gq proteins, leading to the activation of phospholipase C (PLC) and the increase of intracellular calcium, which results in smooth muscle contraction and vasoconstriction. It is predominantly expressed in the smooth muscle cells of blood vessels, kidneys, and the central nervous system. AVPR1A’s role in regulating water retention by the kidneys and controlling blood vessel constriction makes it a key player in maintaining blood pressure and fluid balance. In the brain, AVPR1A is involved in modulating social behaviors, such as bonding and aggression. Dysregulation of AVPR1A is associated with cardiovascular diseases like hypertension, as well as psychiatric conditions such as autism and social anxiety. AVPR1A antagonists are being developed as potential treatments for hypertension, heart failure, and social behavior disorders.
Related Products
Human AVPR1A(Vasopressin V1a receptor) ELISA Kit
Ver Producto
Rat Avpr1a(Vasopressin V1a receptor) ELISA Kit
Ver Producto
Vasopressin V1a Receptor (AVPR1A) Antibody
AVPR1A Antibody is a Rabbit Polyclonal Antibody against AVPR1A.
Ver Producto