Rat Vascular Endothelial Growth Factor C (VEGFC) Protein (Active)

Este producto es parte de VEGFC - Vascular Endothelial Growth Factor C
Rat Vascular Endothelial Growth Factor C (VEGFC) Protein (Active)

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935106861

info@markelab.com

Precio

234€ (2 µg)

Protein VEGFC

proveedor

Abbexa

reference

abx263029

Tested Applications

SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Rat Vascular Endothelial Growth Factor C (VEGFC) Protein, also known as Vascular Endothelial Growth Factor Related Protein (VRP), is a recombinant protein expressed in Sf9 Insect Cells.


Background

VEGFC is primarily responsible for lymphangiogenesis, the formation of lymphatic vessels, by binding to VEGFR-3 on lymphatic endothelial cells During embryonic development and tissue repair, VEGFC promotes the sprouting and maturation of lymphatic vessels VEGFC also activates VEGFR-2 in certain contexts, contributing to angiogenesis and vascular remodeling VEGFC plays a significant role in pathological processes, including cancer metastasis, where it enhances lymphatic vessel growth and facilitates tumor cell dissemination via the lymphatic system Overexpression of VEGFC is observed in various cancers such as breast cancer, melanoma, and prostate cancer, correlating with lymph node metastasis Targeting VEGFC signaling is a promising strategy to inhibit lymphangiogenesis and reduce cancer spread while maintaining tissue fluid balance and immune cell trafficking

Características del producto

category

Proteins and Peptides


origin

Rat


host

Insect


immunogen target

Vascular Endothelial Growth Factor C (VEGFC)


host

Insect


conjugation

Unconjugated


form

Lyophilized Reconstitute in sterile 18 MΩ · cm water to a concentration of at least 100 µg/ml. This stock solution can be further diluted if required.


tested applications

SDS-PAGE


size 1

2 µg


size 2

10 µg


size 3

1 mg


observerd MW

Sequence Fragment: 101-221 AA. Tag: C-terminal His tag


expression

Recombinant


purity

> 90% (SDS-PAGE and RP-HPLC)


buffer

Prior to lyophilization: PBS, containing 50 mg/ml BSA.


storage

Stable at room temperature for up to 3 weeks. It is recommended to store this product desiccated at or below -18 °C. After reconstitution, store at 4 °C for short-term storage (up to 7 days) or below -18 °C for long-term storage. For long-term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles.


or code

VEGFC


dry ice

No


availability

Shipped within 5-10 working days.


alias

VRP,Flt4-L,LMPH1D,LMPHM4,Vascular endothelial growth factor-related protein


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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