Vascular Endothelial Growth Factor C (VEGFC) Antibody Pair
988€ (5 × 96 tests)
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name
Vascular Endothelial Growth Factor C (VEGFC) Antibody Pair
category
Antibody Pairs
provider
Abbexa
reference
abx117420
tested applications
ELISA
Description
VEGFC Antibody Pair for use in Sandwich ELISA assay development. This antibody pair contains the capture antibody and the detection antibody necessary to prepare five 96-well ELISA kit plates.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Antibody Pairs |
| Immunogen Target | Vascular Endothelial Growth Factor C (VEGFC) |
| Reactivity | Human, Rat, Guinea pig, Cow, Horse, Pig, Dog, Goat, Sheep, Duck |
| Assay Data | Capture: Rabbit IgG Polyclonal Detection: Rabbit IgG Polyclonal (Biotin) |
| Assay Type | Sandwich |
| Size 1 | 5 × 96 tests |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| Alias | VRP,Flt4-L,LMPH1D,LMPHM4,Vascular endothelial growth factor-related protein |
| Background | Antibody Pair for VEGFC |
| Status | RUO |
| Note | This product is for research use only. |
Descripción
VEGFC is primarily responsible for lymphangiogenesis, the formation of lymphatic vessels, by binding to VEGFR-3 on lymphatic endothelial cells During embryonic development and tissue repair, VEGFC promotes the sprouting and maturation of lymphatic vessels VEGFC also activates VEGFR-2 in certain contexts, contributing to angiogenesis and vascular remodeling VEGFC plays a significant role in pathological processes, including cancer metastasis, where it enhances lymphatic vessel growth and facilitates tumor cell dissemination via the lymphatic system Overexpression of VEGFC is observed in various cancers such as breast cancer, melanoma, and prostate cancer, correlating with lymph node metastasis Targeting VEGFC signaling is a promising strategy to inhibit lymphangiogenesis and reduce cancer spread while maintaining tissue fluid balance and immune cell trafficking
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