Vascular Endothelial Growth Factor B (VEGFB) Antibody
273€ (100 µl)
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935106861
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name
Vascular Endothelial Growth Factor B (VEGFB) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx103973
tested applications
WB, IHC, IF/ICC
Description
Polyclonal Antibody to Vascular Endothelial Growth Factor B (VEGFB).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Vascular Endothelial Growth Factor B (VEGFB) |
| Host | Rabbit |
| Reactivity | Rat |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | VEGF-B,VEGF-related factor,VRF |
| Background | Antibody anti-VEGFB |
| Status | RUO |
Descripción
VEGFB is a member of the VEGF family that primarily regulates vascular growth and energy metabolism VEGFB binds to VEGFR-1 and Neuropilin-1 (NRP1) to control endothelial cell survival without significantly promoting angiogenesis VEGFB is involved in the transport of fatty acids across endothelial cells into tissues like cardiac muscle and skeletal muscle, where it supports energy homeostasis It is critical for maintaining the health of tissues with high metabolic demand, such as the heart and brain Dysregulation of VEGFB has been linked to metabolic disorders, cardiac hypertrophy, and atherosclerosis Elevated VEGFB expression can protect tissues under ischemic conditions by preserving vascular integrity and promoting fatty acid uptake, making it a potential target for therapeutic interventions in cardiovascular diseases and metabolic syndromes
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