Vascular Endothelial Growth Factor B (VEGFB) Antibody

Este producto es parte de VEGFB - Vascular Endothelial Growth Factor B
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169€ (20 µg)

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935106861
info@markelab.com
name
Vascular Endothelial Growth Factor B (VEGFB) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx318771
tested applications
ELISA, WB, IHC

Description

VEGFB Antibody is a Rabbit Polyclonal against VEGFB.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetVascular Endothelial Growth Factor B (VEGFB)
HostRabbit
ReactivityHuman, Mouse, Rat
Recommended DilutionWB: 1/500 - 1/5000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
Purity> 95%
PurificationPurified by Protein G.
Size 120 µg
Size 250 µg
Size 3100 µg
Size 4200 µg
Size 51 mg
FormLiquid
Tested ApplicationsELISA, WB, IHC
Buffer0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDP49765
Gene ID7423
NCBI AccessionNP_001230662.1, NM_001243733.1, NP_003368.1, NM_003377.4
OMIM601398
AliasVEGF-B,VEGF-related factor,VRF
BackgroundAntibody anti-VEGFB
StatusRUO

Descripción

VEGFB is a member of the VEGF family that primarily regulates vascular growth and energy metabolism VEGFB binds to VEGFR-1 and Neuropilin-1 (NRP1) to control endothelial cell survival without significantly promoting angiogenesis VEGFB is involved in the transport of fatty acids across endothelial cells into tissues like cardiac muscle and skeletal muscle, where it supports energy homeostasis It is critical for maintaining the health of tissues with high metabolic demand, such as the heart and brain Dysregulation of VEGFB has been linked to metabolic disorders, cardiac hypertrophy, and atherosclerosis Elevated VEGFB expression can protect tissues under ischemic conditions by preserving vascular integrity and promoting fatty acid uptake, making it a potential target for therapeutic interventions in cardiovascular diseases and metabolic syndromes
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