Vacuolar protein sorting-associated protein 18 homolog (VPS18) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Vacuolar protein sorting-associated protein 18 homolog (VPS18) Antibody is a Rabbit Polyclonal antibody for the detection of Human VPS18.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Vacuolar protein sorting-associated protein 18 homolog (VPS18) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Size 1 | 20 µl |
| Size 2 | 50 µl |
| Size 3 | 100 µl |
| Size 4 | 200 µl |
| Size 5 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9P253 |
| Gene ID | 57617 |
| OMIM | 608551 |
| Background | Antibody anti-VPS18 |
| Status | RUO |
Descripción
Related Products
VPS18 antibody
Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations(PubMed:11382755, PubMed:23351085, PubMed:24554770, PubMed:25783203). Required for fusion of endosomes and autophagosomes with lysosomes(PubMed:25783203). Involved in dendrite development of Pukinje cells(By similarity).
Ver Producto
Recombinant Human VPS18
Ver Producto
Vacuolar Protein Sorting-Associated Protein 18 Homolog (VPS18) Antibody
VPS18 Antibody is a Rabbit Polyclonal against VPS18.
Ver Producto