V-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog (FOS) Antibody

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273€ (100 µl)

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935106861
info@markelab.com
name
V-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog (FOS) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx128774
tested applications
IHC, IF/ICC

Description

V-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog Antibody is a Rabbit Polyclonal against V-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Target: V-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog (FOS)
Immunogen: FOS (Val55-Phe298)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB (Predicted): 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
Size 1
100 µl
Size 2
200 µl
Size 3
1 ml
Form
Liquid
Tested Applications
IHC, IF/ICC
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-7 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P01100
Background
Antibody anti-FOS
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

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FOS antibody

c-FOS, also named as Proto-oncogene c-Fos and G0/G1 switch regulatory protein 7, is a 380 amino acid protein, which contains 1 bZIP(basic-leucine zipper) domain and belongs to the bZIP family. FOS is expressed at very low levels in quiescent cells. When cells are stimulated to reenter growth, FOS undergo 2 waves of expression, the first one peaks 7.5 minutes following FBS induction. At this stage, the FOS protein is localized endoplasmic reticulum. The second wave of expression occurs at about 20 minutes after induction and peaks at 1 hour. At this stage, the FOS protein becomes nuclear. The calculated molecular weight of FOS is 40 kDa, but Phosphorylated FOS protein is about 60-65 kDa.

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