Uromodulin (UMOD) Antibody
260€ (50 µg)
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name
Uromodulin (UMOD) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx377421
tested applications
ELISA, WB, IHC
Description
Uromodulin (UMOD) Antibody is a Rabbit polyclonal antibody for the detection of Human Uromodulin (UMOD).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Uromodulin (UMOD) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P07911 |
| Gene ID | 7369 |
| NCBI Accession | NP_001008390.1 |
| Background | Antibody anti-UMOD |
| Status | RUO |
Descripción
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UMOD antibody
Uromodulin, also known as THP(Tamm-Horsfall glycoprotein), is the most abundant protein excreted in the urine under physiological conditions. Uromodulin is synthesized by kidney and localizes in cells lining the ascending limb of Henle and distal convoluted tubule. Uromodulin has been linked to water/electrolyte balance and to kidney innate immunity. Also, studies in knockout mice demonstrated that it has a protective role against urinary tract infections and renal stone formation. Mutations in the gene encoding uromodulin lead to rare autosomal dominant diseases, collectively referred to as uromodulin-associated kidney diseases.(PMID: 21654721)
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