Uracil-DNA Glycosylase (UNG) Protein

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Description
UNG Enzyme is an enzyme.
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Uracil-DNA Glycosylase (UNG) |
| Host | E. coli |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 2 kU |
| Size 2 | 10 kU |
| Size 3 | 20 kU |
| Form | Liquid |
| Availability | Shipped within 5-10 working days. |
| Storage | Store below -18°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Background | Protein UNG |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases.
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