935106861
info@markelab.com
Precio
387.5€ (200 µl)
AGTR1 Antibody is a Goat Polyclonal antibody against AGTR1.
AGTR1 is a G-protein-coupled receptor (GPCR) that mediates the majority of the physiological effects of angiotensin II, a key hormone in the renin-angiotensin-aldosterone system (RAAS). It is primarily expressed in tissues such as the heart, kidneys, vascular smooth muscle, and adrenal glands, where it regulates critical functions including blood pressure, fluid balance, and vascular tone. Upon activation by angiotensin II, AGTR1 initiates signaling cascades involving Gq proteins, which increase intracellular calcium levels and activate pathways such as protein kinase C (PKC), mitogen-activated protein kinase (MAPK), and reactive oxygen species (ROS) generation.
Primary Antibodies
Polyclonal
Human, Mouse
Type-1 Angiotensin II Receptor (AGTR1)
Goat
Unconjugated
Liquid
P-ELISA, WB
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
200 µl
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
AGTR1
No
Shipped within 1-3 working days.
AGTR1,AG2S, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, ATR1, HAT1R,angiotensin II type-1 receptor
NP_000676.1, NP_004826.2, NP_033611.1, NP_114038.1, NP_114438.1
This product is for research use only.
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