Type-1 Angiotensin II Receptor (AGTR1) Antibody

Este producto es parte de AGTR1 - Angiotensin II receptor type 1
Type-1 Angiotensin II Receptor (AGTR1) Antibody

Pida mas información

935106861

info@markelab.com

Precio

416€ (200 µl)

Antibody anti-AGTR1

proveedor

Abbexa

reference

abx430326

Tested Applications

P-ELISA, WB

reactivity

Human, Mouse

status

RUO

clonality

Polyclonal

Descripción

AGTR1 Antibody is a Goat Polyclonal antibody against AGTR1.

Background

AGTR1 is a G-protein-coupled receptor (GPCR) that mediates the majority of the physiological effects of angiotensin II, a key hormone in the renin-angiotensin-aldosterone system (RAAS). It is primarily expressed in tissues such as the heart, kidneys, vascular smooth muscle, and adrenal glands, where it regulates critical functions including blood pressure, fluid balance, and vascular tone. Upon activation by angiotensin II, AGTR1 initiates signaling cascades involving Gq proteins, which increase intracellular calcium levels and activate pathways such as protein kinase C (PKC), mitogen-activated protein kinase (MAPK), and reactive oxygen species (ROS) generation.

Características del producto

category

Primary Antibodies

clonality

Polyclonal

reactivity

Human, Mouse

immunogen target

Type-1 Angiotensin II Receptor (AGTR1)

host

Goat

isotype

IgG

conjugation

Unconjugated

form

Liquid

tested applications

P-ELISA, WB

purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

recommended dilution

P-ELISA: 1/32000. Optimal dilutions/concentrations should be determined by the end user.

buffer

Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.

size 1

200 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

AGTR1

dry ice

No

availability

Shipped within 5-10 working days.

alias

AGTR1,AG2S, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, ATR1, HAT1R,angiotensin II type-1 receptor

gene id

https://www.ncbi.nlm.nih.gov/gene/185https://www.ncbi.nlm.nih.gov/gene/11607https://www.ncbi.nlm.nih.gov/gene/24180

NCBI accession

NP_000676.1, NP_004826.2, NP_033611.1, NP_114038.1, NP_114438.1

note

Concentration: 0.5 mg/ml -

Quizá le pueda interesar

Human AGTR1(Type-1 angiotensin II receptor) ELISA Kit

Human AGTR1(Type-1 angiotensin II receptor) ELISA Kit

proveedor

FineTest

reference

EH1872

reactivity

human

status

RUO

Precio a consultar

Ver más

Mouse Agtr1b(Type-1B angiotensin II receptor) ELISA Kit

Mouse Agtr1b(Type-1B angiotensin II receptor) ELISA Kit

proveedor

FineTest

reference

EM0801

reactivity

mouse

status

RUO

Precio a consultar

Ver más

Mouse AT1R (angiotensin Ⅱ receptor type 1) ELISA Kit

Mouse AT1R (angiotensin Ⅱ receptor type 1) ELISA Kit

proveedor

FineTest

reference

EM1911

reactivity

mouse

status

RUO

Precio a consultar

Ver más