Tumor Protein P53-Inducible Nuclear Protein 1 (TP53INP1) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Tumor Protein P53-Inducible Nuclear Protein 1 (TP53INP1) Antibody is a Rabbit polyclonal antibody for the detection of Human Tumor Protein P53-Inducible Nuclear Protein 1 (TP53INP1).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Tumor Protein P53-Inducible Nuclear Protein 1 (TP53INP1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96A56 |
| Gene ID | 94241 |
| NCBI Accession | NP_001129205.1 |
| Background | Antibody anti-TP53INP1 |
| Status | RUO |
Descripción
Related Products
TP53INP1 antibody
Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response. Possesses both a p53/TP53-independent intracellular reactive oxygen species(ROS) regulatory function and a p53/TP53-dependent transcription regulatory function. Positively regulates p53/TP53 and p73/TP73 and stimulates their capacity to induce apoptosis and regulate cell cycle. In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis. Acts as a tumor suppressor by inducing cell death by an autophagy and caspase-dependent mechanism. Can reduce cell migration by regulating the expression of SPARC.
Ver Producto
Tumor Protein P53-Inducible Nuclear Protein 1 (TP53INP1) Antibody
TP53INP1 Antibody is a Rabbit Polyclonal Antibody against TP53INP1.
Ver Producto
Tumor Protein P53-Inducible Nuclear Protein 1 (TP53INP1) Antibody
Rabbit polyclonal antibody against TP53INP1 protein. Immunogen region is C-terminal.
Ver Producto