Tumor Necrosis Factor Receptor Superfamily Member 4 / CD134 (TNFRSF4) Antibody
299€ (0.1 mg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Tumor Necrosis Factor Receptor Superfamily Member 4 / CD134 (TNFRSF4) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx139929
Tested Applications
ELISA, WB, IHC, FCM, IP
Description
CD134 Antibody is a Mouse Monoclonal against CD134.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Tumor Necrosis Factor Receptor Superfamily Member 4 / CD134 (TNFRSF4) Immunogen: HTLV 1-transformed HUT-102 cells. |
| Host | Mouse |
| Reactivity | Human, Monkey |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 Kappa |
| Clone ID | O283 |
| Purity | > 95% (SDS-PAGE) |
| Purification | Purified by Protein A affinity chromatography. |
| Size 1 | 0.1 mg |
| Tested Applications | ELISA, WB, IHC, FCM, IP |
| Buffer | PBS solution with 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8°C. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P43489 |
| Gene ID | 7293 |
| Alias | OX40,ACT35,CD134,IMD16,TXGP1L,OX40L receptor,TAX transcriptionally-activated glycoprotein 1 receptor |
| Background | Antibody anti-TNFRSF4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
TNFRSF4, commonly known as OX40 (CD134), is a member of the tumor necrosis factor receptor (TNFR) superfamily. It is an important costimulatory molecule expressed on T cells, specifically induced upon T cell activation. TNFRSF4 is known for its involvement in regulating immune responses, especially in T-cell proliferation, survival, and memory formation. As an immune-regulatory receptor, it primarily interacts with its ligand, OX40L (TNFSF4), which is expressed on antigen-presenting cells (APCs), such as dendritic cells, B cells, and macrophages. OX40’s role in immune modulation is significant because it amplifies T-cell responses during both acute infections and in chronic immune responses, such as autoimmune diseases and cancer. By sustaining T-cell activation and enhancing immune memory, OX40 has become a central target in immunotherapy research, especially in the contexts of cancer immunotherapy and autoimmune diseases. Its ability to promote prolonged immune responses also makes it a critical regulator in various immune-related diseases, where modulation of OX40-OX40L interactions can potentially benefit patient outcomes.
Productos relacionados
Tumor Necrosis Factor Receptor Superfamily Member 4 / CD134 (TNFRSF4) Antibody
TNFRSF4 Antibody is a Rabbit Polyclonal antibody against TNFRSF4. The protein encoded by this gene is a member of the TN…
Ver producto
Tumor Necrosis Factor Receptor Superfamily Member 4 / CD134 (TNFRSF4) Antibody
TNFRSF4 Antibody is a Rabbit Polyclonal Antibody against TNFRSF4.…
Ver producto