Tumor Necrosis Factor Ligand Superfamily, Member 12 (TNFSF12) Antibody
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Description
Tumor Necrosis Factor Ligand Superfamily, Member 12 (TNFSF12) Antibody is a Rabbit Polyclonal Antibody against Tumor Necrosis Factor Ligand Superfamily, Member 12 (TNFSF12) for use in flow cytometry.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Tumor Necrosis Factor Ligand Superfamily, Member 12 (TNFSF12) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | FCM: 1-5 µl/106 cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen-specific affinity chromatography. |
| Size 1 | 50 tests |
| Size 2 | 100 tests |
| Size 3 | 200 tests |
| Size 4 | 500 tests |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Please enquire. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Background | Antibody anti-TNFSF12 |
| Status | RUO |
Descripción
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The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.
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TNFSF12 Antibody is a Rabbit Polyclonal antibody against TNFSF12. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants.
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