Tumor Necrosis Factor-Inducible Gene 6 Protein (TNFAIP6) Antibody

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Description
Tumor Necrosis Factor-Inducible Gene 6 Protein (TNFAIP6) Antibody is a Rabbit polyclonal antibody for the detection of Human Tumor Necrosis Factor-Inducible Gene 6 Protein (TNFAIP6).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Tumor Necrosis Factor-Inducible Gene 6 Protein (TNFAIP6) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P98066 |
| Gene ID | 7130 |
| NCBI Accession | NP_009046.2 |
| Background | Antibody anti-TNFAIP6 |
| Status | RUO |
Descripción
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The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.
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